I'm surprised this worked since the crash started happening initially on a fresh Steam and Civ installation on a new computer. I resolved my crash by uninstalling Civilization 5, then uninstalling Steam, then reinstalling. Uninstall and reinstall Civilization 5.Try loading from the Mods menu instead of the main menu.Delete the Saves and Cache folders in My Games \ Civ 5.Create a new game, save it, then try to load.Copy saved games from a different (working) computer.Steam Library > Properties > Local Files > Verify Integrity of Game Cache.Clean uninstall/reinstall of display driver.The is a newly installed & brawny laptop. I'm running under Steam on 64-bit Windows 7 Professional. I've played Civ 5 for years on 3 other computers without this problem. I can load games with Steam is in Offline mode, but I want to save to the cloud, and also to stay online for other games. It's discussed widely in forums, but the proposed solutions don't work for me (or for many other people). Please contact the application's support team for more information. This application has requested the Runtime to terminate it in an unusual way. apps\common\Sid Meier's Civilization V\Civilization.exe I click Single Player > Load Game and immediately see this dialog: Microsoft Visual C++ Runtime Library
